Browsing by Author "Özcan, Alper"
Now showing items 1-3 of 3
-
Alantolactone ameliorates graft versus host disease in mice
Odabas, Gul Pelin; Aslan, Kubra; Suna, Pinar Alisan; Kendirli, Perihan Kader; Erdem, Şerife; Çakır, Mustafa; Özcan, Alper; Yılmaz, Ebru; Karakukcu, Musa; Donmez-Altuntas, Hamiyet; Yay, Arzu Hanim; Deniz, Kemal; Altay, Derya; Arslan, Duran; Canatan, Halit; Eken, Ahmet; Unal, Ekrem (Elsevier B.V., 15 Februar)The anti-inflammatory and immunosuppressive drugs which are used in the treatment of Graft-versus-Host Disease (GVHD) have limited effects in controlling the severity of the disease. In this study, we aimed to investigate ... -
Correction to: a novel biallelic lck variant resulting in profound t-cell ımmune deficiency and review of the literature
Lanz, Anna Lisa; Erdem, Şerife; Özcan, Alper; Ceylaner, Gülay; Cansever,Murat; Ceylaner, Serdar; Conca, Raffaele; Magg, Thomas; Acuto, Oreste; Latour, Sylvain; Klein, Christoph; Patiroglu, Turkan; Unal, Ekrem; Eken, Ahmet; Hauck, Fabian (Springer, January 20)Lymphocyte-specific protein tyrosine kinase (LCK) is an SRC-family kinase critical for initiation and propagation of T-cell antigen receptor (TCR) signaling through phosphorylation of TCR-associated CD3 chains and recruited ... -
Pyruvate kinase deficiency in 29 Turkish patients with two novel intronic variants
Gök, Veysel; Leblebisatan, Göksel; Gökçebay, Dilek Gürlek; Güler, Salih; Doğan, Muhammet Ensar; Bozdoğan, Sevcan Tuğ; Yozgat, Ayca Koca; Özcan, Alper; Şahinoğlu, Esra Pekpak; Tokgöz, Hüseyin; Çil, Metin; Sağ, Şebnem Özemri; Yılmaz, Ebru; Şaşmaz, Hatice İlgen; Evim, Melike Sezgin; Akbayram, Sinan; Karadoğan, Meriban; Mutlu, Fatma Türkan; Boğa, İbrahim; Doğan, Burcu Yeter; Yaralı, Neşe; Çalışkan, Uemran; Bisgin, Atıl; Temel, Sehime Gülsun; Kanıtlanmış, Melanie; Gibson, Kate; Demir, Buesra Şeniz; Saraçoğlu, Hatice; Eken, Ahmet; Karakukcu, Çiğdem; Karakükçü, Musa; Güneş, Adalet Meral; Özbek, Namık Yaşar; Kılınç, Yurdanur; Patıroğlu, Tuerkan; Özdemir, Mehmet Akif; Roy, Noemi BA; Ünal, Ekrem (Wiley, MAY 2024)Pyruvate kinase (PK) is a key enzyme of anaerobic glycolysis. The genetic heterogeneity of PK deficiency (PKD) is high, and over 400 unique variants have been identified. Twenty-nine patients who had been diagnosed as PKD ...
