Browsing by Author "Unal, Ekrem"
Now showing items 1-6 of 6
-
30 years of wilms tumor experience at one center in türkiye's central anatolia region
Akyol, Sefika; Odabas, Gul Pelin; Ozcan, Alper; Yilmaz, Ebru; Karaman, Zehra Filiz; Ozturk, Figen; Akgun, Huelya; Dogan, Ahmet Burak; Eroglu, Celalettin; Unal, Ekrem; Karakukcu, Musa (İstanbul Üniv., 2023)Objective: The current study aims to evaluate the clinical presentation, treatment, and follow-up of children with Wilms Tumor (WT) who had been admitted to Erciyes University, Faculty of Medicine Department of Pediatric ... -
Alantolactone ameliorates graft versus host disease in mice
Odabas, Gul Pelin; Aslan, Kubra; Suna, Pinar Alisan; Kendirli, Perihan Kader; Erdem, Şerife; Çakır, Mustafa; Özcan, Alper; Yılmaz, Ebru; Karakukcu, Musa; Donmez-Altuntas, Hamiyet; Yay, Arzu Hanim; Deniz, Kemal; Altay, Derya; Arslan, Duran; Canatan, Halit; Eken, Ahmet; Unal, Ekrem (Elsevier B.V., 15 Februar)The anti-inflammatory and immunosuppressive drugs which are used in the treatment of Graft-versus-Host Disease (GVHD) have limited effects in controlling the severity of the disease. In this study, we aimed to investigate ... -
Correction to: a novel biallelic lck variant resulting in profound t-cell ımmune deficiency and review of the literature
Lanz, Anna Lisa; Erdem, Şerife; Özcan, Alper; Ceylaner, Gülay; Cansever,Murat; Ceylaner, Serdar; Conca, Raffaele; Magg, Thomas; Acuto, Oreste; Latour, Sylvain; Klein, Christoph; Patiroglu, Turkan; Unal, Ekrem; Eken, Ahmet; Hauck, Fabian (Springer, January 20)Lymphocyte-specific protein tyrosine kinase (LCK) is an SRC-family kinase critical for initiation and propagation of T-cell antigen receptor (TCR) signaling through phosphorylation of TCR-associated CD3 chains and recruited ... -
DIAPH1-deficiency is associated with major t, nk and ılc defects in humans
Azizoglu, Zehra Busra; Babayeva, Royala; Haskologlu, Zehra Sule; Acar, Mustafa Burak; Ayaz-Guner, Serife; Okus, Fatma Zehra; Alsavaf, Mohammad Bilal; Can, Salim; Basaran, Kemal Erdem; Canatan, Mehmed Fatih; Ozcan, Alper; Erkmen, Hasret; Leblebici, Can Berk; Yilmaz, Ebru; Karakukcu, Musa; Kose, Mehmet; Canoz, Ozlem; Özen, Ahmet; Karakoc-Aydiner, Elif; Ceylaner, Serdar; Gümüş, Gülsüm; Per, Huseyin; Gumus, Hakan; Canatan, Halit; Ozcan, Servet; Dogu, Figen; Ikinciogullari, Aydan; Unal, Ekrem; Baris, Safa; Eken, Ahmet (Springer, December 2)Loss of function mutations in Diaphanous related formin 1 (DIAPH1) are associated with seizures, cortical blindness, and microcephaly syndrome (SCBMS) and are recently linked to combined immunodeficiency. However, the ... -
Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis
Chiang, Samuel C. C.; Covill, Laura E.; Tesi, Bianca; Campbell, Tessa M.; Schlums, Heinrich; Nejati-Zendegani, Jelve; Mördrup, Karina; Wood, Stephanie; Theorell, Jakob; Sekine, Takuya; Al-Herz, Waleed; Akar, Himmet Haluk; Unal, Ekrem (Elsevier B.V., 2024)Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for ... -
Rare coagulation factor deficiencies: Multicenter experience with 188 cases
Gok, Veysel; Sahinoglu, Esra Pekpak; Tokgoz, Hueseyin; Mutlu, Fatma Turkan; Acipayam, Can; Karaman, Kamuran; Tuncel, Defne Ay; Oren, Ayse Ceyda; Simsek, Ayse; Arslan, Bilal; Unal, Hatice Beyza; Ozcan, Alper; Yilmaz, Ebru; Akbayram, Sinan; Karakukcu, Musa; Oner, Ahmet Fayik; Caliskan, Umran; Patiroglu, Turkan; Unal, Ekrem (İstanbul Üniv., 2024)Objective: Rare factor deficiencies are a group of autosomal recessive bleeding disorders (with the exception of dysfibrinogenemia), which are characterized by the deficiency or dysfunction of one or more coagulation factors ...
