Electrochemical Tau Protein Immunosensor Based on MnS/GO/PANI and Magnetite-incorporated Gold Nanoparticles
| dc.contributor.author | Yola, Bahar Bankoglu | |
| dc.contributor.author | Karaman, Ceren | |
| dc.contributor.author | Ozcan, Nermin | |
| dc.contributor.author | Atar, Necip | |
| dc.contributor.author | Polat, Ilknur | |
| dc.contributor.author | Yola, Mehmet Lutfi | |
| dc.date.accessioned | 2022-07-21T08:10:03Z | |
| dc.date.available | 2022-07-21T08:10:03Z | |
| dc.date.issued | MAY 2022 | en_US |
| dc.department | HKÜ, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü | en_US |
| dc.description.abstract | Herein, electrochemical tau protein immunosensor based on manganese sulfide nanoparticles/graphene oxide/polyaniline (MnS/GO/PANI) and magnetite-incorporated gold nanoparticles (AuNPs@Fe3O4) was constructed. After the modification of the glassy carbon electrode (GCE) with MnS/GO/PANI, the immobilization and conjugation of anti-Tau capture antibody and antigen Tau protein were successfully completed on MnS/GO/PANI/GCE, respectively. Then, the conjugation of anti-Tau secondary antibody was carried out to AuNPs@Fe3O4 as signal amplification via amino-gold affinity and the eventual immunosensor was accomplished by the distinctive interactions of electrode platform and signal amplification. Final immunosensor demonstrated the quantification limit (LOQ) of 1.0x10(-13) M and the detection limit (LOD) of 1.0x10(-14) M. | en_US |
| dc.identifier.citation | Yola, B., Karaman, C., Ozcan, N., Atar, N., Polat, I., & Yola, M. (April 26, 2022). Electrochemical tau protein immunosensor based on MnS/GO/PANI and magnetite-incorporated gold nanoparticles. Electroanalysis. | en_US |
| dc.identifier.doi | 10.1002/elan.202200159 | |
| dc.identifier.issn | 1040-0397 | |
| dc.identifier.issn | 1521-4109 | |
| dc.identifier.orcid | 0000-0001-7424-3425 | en_US |
| dc.identifier.scopus | 2-s2.0-85132639280 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.uri | https://doi.org/10.1002/elan.202200159 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.11782/2594 | |
| dc.identifier.wos | WOS:000796554300001 | |
| dc.identifier.wosquality | Q2 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | WILEY-V C H VERLAG GMBH | en_US |
| dc.relation.ispartof | ELECTROANALYSIS | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Detection | en_US |
| dc.subject | Detection | en_US |
| dc.subject | Voltammetry | en_US |
| dc.subject | Diagnosis | en_US |
| dc.subject | Alzheimer's disease | en_US |
| dc.title | Electrochemical Tau Protein Immunosensor Based on MnS/GO/PANI and Magnetite-incorporated Gold Nanoparticles | |
| dc.type | Article |
